Immunohistochemistry Kits and Reagents
ABclonal Technology HBG1 Rabbit pAb
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is 5-epsilon -- gamma-G -- gamma-A -- delta -- beta--3.
ABclonal Technology Phospho-p38 MAPK-T180
The protein encoded by this gene is a member of the MAP kinase family MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development This kinase is activated by various environmental stresses and proinflammatory cytokines The activation requires its phosphorylation by MAP kinase kinases (MKKs) or its autophosphorylation triggered by the interaction of MAP3K7IP1 TAB1 protein with this kinase The substrates of this kinase include transcription regulator ATF2 MEF2C and MAX cell cycle regulator CDC25B and tumor suppressor p53 which suggest the roles of this kinase in stress related transcription and cell cycle regulation as well as in genotoxic stress response Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
ABclonal Technology AIF1/IBA1 Rabbit pAb
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain.
Biotium CDw78(DF1588), CF594 conjugate, 0.1mg/mL
This antibody reacts with a carbohydrate determinant, identified as CDw78 (Workshop V; Code CDw78.2). Epitope recognized by this MAb and Leu21 is the same. It is present on some immature and some peripheral blood B cells, and some B cell lines. Its expression is increased after B-cell activation in vitro. CDw78 is also found on tissue macrophages and on epithelial cells, but not on T cells, NK cells, monocytes, granulocytes and myeloid tissues. It appears that CDw78 is a determinant on a major histocompatibility complex (MHC) class II subpopulation.
Meso Scale Discovery R-PLEX Human Calbindin ASYQP
The R-Plex Human Calbindin Assay from Meso Scale Diagnostics is a multiplex immunoassay measuring calbindin in human serum plasma urine and other matrices It uses electrochemiluminescence (ECL) detection for high sensitivity a wide dynamic range and low sample volume This assay quantifies calbindin a calcium-binding protein in the intestine and kidneys aiding in diagnosing diseases related to calbindin levels The kit includes a 96-well plate with capture antibodies detection antibodies calibrators and necessary reagents
Meso Scale Discovery RPLEX HUM FABP3/HFABP ASYQP
The R-PLEX Human FABP3 (H-FABP) Assay Kit from Meso Scale Diagnostics is used to quantitatively measure human heart-type fatty acid binding protein (H-FABP) in serum plasma cell culture supernatants cell and tissue lysates using an electrochemiluminescent detection technology The assay has high sensitivity and wide dynamic range This multiplex kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer sample diluent calibrator diluent and lyophilized calibrator The assay takes 3 5 hours to complete
Sino Biological Anti-Claudin 18.2 (Research Grade Zolbetuximab Biosimilar) 5 mg
This product is a recombinant monoclonal antibody expressed from HEK293 cells.